EED antibody

Catalogue Number: GTX14294-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:50
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:embryonic ectoderm development , COGIS , HEED , WAIT1
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Immunogen Sequence: GI # 24041020, sequence 41-168 Recombinant embryonic ectoderm development isoform a
Application: WB

Description

Description: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta7, immunodeficiency virus type 1 (HIV1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Four transcript variants encoding distinct isoforms have been identified for this gene. The four isoforms are differentialy expressed during ES cell differentiation, with four isoforms intially expressed. Only isoform 3 then remains after differentiation.

Additional Text

Gene Name

EED

Uniprot ID

O75530

Purification

Affinity Purified

Gene ID

8726

Molecular Weight

50

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.