Dynamin 1 antibody [4E67]

Catalogue Number: GTX14448-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:97
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:DNM , DNM1 , EIEE31 , dynamin 1 , Dynamin 1
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Mouse
Clone: 4E67
Isotype: IgG1
Immunogen: Recombinant His 6-tagged human dynamin (aa1-750). Epitope: GNRGMEDLIPLVNRLQD.
Application: FC, IP, WB, IHC

Description

Description: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

1759

Gene Name

DNM1

Uniprot ID

Q05193

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

97

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 0.5µg/ml. FCM: 10µg/ml. IHC: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.