PDE1C antibody

Catalogue Number: GTX14602-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:81
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:phosphodiesterase 1C , DFNA74 , Hcam3 , cam-PDE 1C , hCam-3
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on PDE1C gene.
Application: ELISA, ICC, IF, IP, WB, IHC

Description

Description: This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. [provided by RefSeq, Jul 2016]

Additional Text

Concentration

0.5 mg/ml

Gene Name

PDE1C

Uniprot ID

Q14123

Purification

Affinity Purified

Gene ID

5137

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

81

Application Notes

WB: 1:500-1:2000. ICC/IF: 1:40-1:100. IP: 1:200. ELISA: 1:10000. IHC: 1:40-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.