TCR V gamma 1.1 antibody [2.11]

Catalogue Number: GTX14669-GTX

Manufacturer:	GeneTex
Preservative:	no preservative\|No preservative
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	T cell receptor gamma chain,TCRGV1S1,TCRGV2S1,TCRGV3S1,TCRGV5S3,Tcrg
Shipping Condition:	Blue Ice
Unit(s):	250 ug
Host name:	Armenian Hamster
Clone:	2.11
Isotype:	IgG
Immunogen:	3.13.1 T cell hybridoma
Application:	FC

Overview
Datasheets

Description

Description: T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase. [provided by RefSeq, Jul 2008]

Additional Text

Purification

Protein G purified

Gene ID

110067

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Gene Name

Tcrg

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.

GTX14669 Datasheet

Price

£216.00

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