Catalogue Number: GTX14784-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 117 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | natriuretic peptide receptor 2 , AMDM , ANPRB , ANPb , ECDM , GUC2B , GUCY2B , NPRB , NPRBi , SNSK |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase B protein. |
| Application: | ELISA, ICC, IF, IP, WB, IHC |
Description: This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
4882
P20594
Affinity Purified
117
NPR2
Polyclonal
0.75-1.20 mg/ml
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
WB: 1:500. ICC/IF: 1:200. IP: 1:200. ELISA: 1:10000. IHC: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.