BMP2 antibody

Catalogue Number: GTX14933-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:45
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:bone morphogenetic protein 2 , AI467020 , Bmp2a
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide corresponding to Mouse BMP2 amino acid region 45-60 conjugated to Keyhole Limpet Haemocyanin (KLH). Sequence:SEDVLSEFELRLLSMF
Application: ELISA, ICC, IF, IHC-P, IP, WB, IHC-Fr, DB

Description

Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. While a homozygous knockout mouse for this gene exhibits embryonic lethality, conditional knockout mice have defects in bone, cartilage and heart development. [provided by RefSeq, Jul 2016]

Additional Text

Uniprot ID

P21274

Gene Name

BMP2

Concentration

0.73 mg/ml

Purification

Affinity Purified

Molecular Weight

45

Gene ID

12156

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:200. ICC/IF: 1:2000. IP: 1:200-1:500. ELISA: 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.