alpha 2 Macroglobulin antibody [F1-P1C11 #3]
Catalogue Number: GTX15643-GTX
GTX15643 Image
GTX15643 Image
GTX15643 Image
GTX15643 Image
WB analysis of 1000ng, 500ng, 250ng and 125ng of a human alpha 2 Macroglobulin recombinant protein using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3]. Dilution : 2 µg/ml
GTX15643 Image
WB analysis of 5ul of human plasma using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3]. Dilution : 1 µg/ml
GTX15643 Image
ELISA analysis of Alpha2-Macroglobulin recombinant protein diluted in carbonate/bicarbonate buffer (1 µg/ml, 100µl/well) using GTX15643 alpha 2 Macroglobulin antibody [F1-P1C11 #3] at 0.03125 - 2 µg/mL (serial diluted).
| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 163 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | alpha-2-macroglobulin , A2MD , CPAMD5 , FWP007 , S863-7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | F1-P1C11 #3 |
| Isotype: | IgG1 |
| Immunogen: | Purified human plasma AMG |
| Application: | ELISA, IP, WB, RIA |
Description
Description: The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
Additional Text
Uniprot ID
P01023
Gene ID
2
Gene Name
A2M
Molecular Weight
163
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
WB: 1-2 µg/ml. ELISA: 2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX15643 Datasheet
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