Apolipoprotein B antibody [F2C9]

Catalogue Number: GTX15662-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	516
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	apolipoprotein B , FLDB , LDLCQ4 , apoB-100 , apoB-48
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	F2C9
Isotype:	IgG1
Immunogen:	Purified human serum LDL
Application:	ELISA, IP, RIA

Overview
Datasheets

Description

Description: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

APOB

Uniprot ID

P04114

Gene ID

338

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX15662 Datasheet

Price

£410.00

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