TNF alpha antibody [XT3]

Catalogue Number: GTX15821-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:26
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:tumor necrosis factor , DIF , TNF-a , TNF-alpha , TNFSF2 , TNFalpha , Tnfa , Tnfsf1a , Tnlg1f
Shipping Condition:Blue Ice
Unit(s): 250 ug
Host name: Rat
Clone: XT3
Isotype: IgG1
Immunogen: Recombinant mouse TNF alpha
Application: ELISA, IHC-P, sELISA, WB, IHC, NT, Inh

Description

Description: This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Additional Text

Uniprot ID

P06804

Gene Name

TNF

Gene ID

21926

Purification

Ammonium Sulfate Precipitated

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

26

Concentration

1 mg/ml

Application Notes

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.