AMACR antibody

Catalogue Number: GTX15893-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:alpha-methylacyl-CoA racemase , AMACRD , CBAS4 , P504S , RACE , RM
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Synthetic peptide taken within amino acid region 50-100 on human alpha-methylacyl-CoA racemase protein.
Application: ELISA, ICC, IF, IHC-P, IP, WB

Description

Description: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011]

Additional Text

Gene Name

AMACR

Molecular Weight

42

Concentration

0.6 mg/ml

Gene ID

23600

Purification

Affinity Purified

Uniprot ID

Q9UHK6

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:500. ICC/IF: 1:100. IP: 1:200. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.