IL6 antibody [AS16] (Biotin)

Catalogue Number: GTX16164-GTX

Manufacturer:GeneTex
Preservative:0.08% Sodium azide|0.08% Sodium azide
Molecular Weight:24
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:interleukin 6 , BSF-2 , BSF2 , CDF , HGF , HSF , IFN-beta-2 , IFNB2 , IL-6
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: AS16
Isotype: IgG1
Immunogen: Unfortunately, this information is considered to be commercially sensitive
Application: ELISA

Description

Description: This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Additional Text

Gene Name

IL6

Gene ID

3569

Uniprot ID

P05231

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

ELISA: This antibody has been used as a solution-phase antibody at 2 µg/ml in a two-site ELISA with unconjugated IL6 antibody. Typicallly, the ELISA has a working range of 0-10000 pg/ml and sensitivity 5 pg/ml with the appropriate standard. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.