CD8 alpha antibody [53-6.7] (FITC)

Catalogue Number: GTX16189-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:26
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD8a molecule , CD8 , Leu2 , p32
Shipping Condition:Blue Ice
Unit(s): 125 ug
Host name: Rat
Clone: 53-6.7
Isotype: IgG2a
Immunogen: Human PBMCs stimulated with PHA.
Application: FC, ICC, IF, IHC-Fr

Description

Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Additional Text

Gene ID

925

Gene Name

CD8A

Uniprot ID

P01732

Concentration

0.5 mg/ml

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

FACS: Use at an assay dependent dilution. IF: Use at a dilution of 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.