TNF Receptor I antibody [HM104] (PE)

Catalogue Number: GTX16198-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:50
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:tumor necrosis factor receptor superfamily, member 1a , CD120a , FPF , TNF-R , TNF-R-I , TNF-R1 , TNF-R55 , TNF-alphaR1 , TNFAR , TNFR60 , TNFRI , TNFRp55 , TNFalpha-R1 , Tnfr-2 , Tnfr1 , p55 , p55-R
Shipping Condition:Blue Ice
Unit(s): 500 ul
Host name: Rat
Clone: HM104
Isotype: IgG2a
Immunogen:
Application: FC, ICC, IF

Description

Description: This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]

Additional Text

Gene Name

TNFRSF1A

Uniprot ID

P25118

Concentration

0.1 mg/ml

Gene ID

21937

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.