Phosphotyrosine antibody [PY20] (Biotin)

Catalogue Number: GTX16388-GTX

Manufacturer:GeneTex
Preservative:3 mM Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: PY20
Isotype: IgG2b
Immunogen: Phosphotyrosine coupled to carrier protein
Application: ELISA, ICC, IF, WB, IHC

Description

Description: The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research.

Additional Text

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

ELISA: 1/5000. ICC: 1/500. WB: 1/5000. IHC: 1/500. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.