HP1 gamma antibody [5G10-F7-A12]
Catalogue Number: GTX16488-GTX
GTX16488 Image
GTX16488 Image
GTX16488 Image
GTX16488 Image
GTX16488 Image
ICC/IF analysis of HeLa cells using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:200.
GTX16488 Image
IHC-P analysis of prostate cancer using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:200. Antigen retrieval was performed by pressure cooking in citrate buffer (pH 6.0).
GTX16488 Image
IP analysis was performed with HeLa lysates and either control IgG PR HP1 gamma antibody [5G10-F7-A12]. The precipitates were detected by the same antibody.
GTX16488 Image
WB analysis of various cell lysates using HP1 gamma antibody [5G10-F7-A12] at a dilution of 1:1000.
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 21 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | chromobox 3 , HECH , HP1-GAMMA , HP1Hs-gamma |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 5G10-F7-A12 |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant human HP1-gamma protein fragments expressed in E.coli. |
| Application: | ICC, ID, IF, IHC-P, IP, WB |
Description
Description: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
Additional Text
Gene ID
11335
Gene Name
CBX3
Uniprot ID
Q13185
Purification
Affinity Purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
21
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX16488 Datasheet
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