TGF beta Receptor antibody
Catalogue Number: GTX17282-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.08% Sodium azide|0.08% Sodium azide |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Transforming growth factor beta receptor II (70-80kDa) , TGF beta receptor , Transforming growth factor beta receptor II , TGF beta receptor type II precursor , TGF beta type II receptor , Transforming growth factor beta receptor II (7080kDa) , TGFR2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Sheep |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | GST fusion avian protein, containing chick transforming growth factor b type II receptor (aa 77 - 148). |
| Application: | WB, IHC |
Description
Description: Three members of the TGF beta family, TGF beta 1, TGF beta 2 and TGF beta 3, are known in mammals. TGF betas mediate their activity by high affinity binding to the type 2 receptor, which requires both its kinase activity and association with members of a series of related type 1 receptors called activin receptor-like kinase (ALK) 1 to 6. Of these, only ALK5 has been shown to represent a functional TGF beta type 1 receptor, but only ALK2 and ALK4 bind activin with high affinity. TGF beta R3 binds TGF beta and retains TGF beta for presentation to the signaling receptors.
Additional Text
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
IHC: Use at an assay dependent dilution. WB: 1/100. Predicted molecular weight: 68 kDa. Optimal dilutions/concentrations should be determined by the end user.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX17282 Datasheet
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