BAFF antibody [Buffy-1] (FITC)
Catalogue Number: GTX17329-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 31 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | TNF superfamily member 13b , BAFF , BLYS , CD257 , DTL , TALL-1 , TALL1 , THANK , TNFSF20 , TNLG7A , ZTNF4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 tests |
| Host name: | Rat |
| Clone: | Buffy-1 |
| Isotype: | IgG2a |
| Immunogen: | BAFF (monoclonal Buffy-1) antibody was raised against recombinant human soluble BAFF (aa. 83-285). |
| Application: | FC |
Description
Description: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL,THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis.
Additional Text
Gene Name
TNFSF13B
Gene ID
10673
Uniprot ID
Q9Y275
Purification
Purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. Protect from light.
Application Notes
FCM: 4 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX17329 Datasheet
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