Human Tau (K18) protein, mutant P301L (Pre-formed Fibrils)
Catalogue Number: GTX17675-PRO-GTX
GTX17675-PRO Image
GTX17675-PRO Image
GTX17675-PRO Image
GTX17675-PRO Image
GTX17675-PRO Image
Thioflavin T is a fluorescent dye that binds to beta sheet-rich structures, such as those in tau fibrils. Upon binding, the emission spectrum of the dye experiences a red-shift and increased fluorescence intensity. Thioflavin T emission curves show increased fluorescence (correlated to tau aggregation) over time in tau preformed fibrils (GTX17675-pro). Tau preformed fibrils (GTX17675-pro) seed the formation of new tau fibrils when combined with tau monomers (GTX17672-pro). Thioflavin T ex = 450 nm, em = 485 nm.
GTX17675-PRO Image
SDS-PAGE of ~15 kDa Human Tau (K18) protein, mutant P301L (preformed fibrils (PFFs)) (GTX17675-pro). Lane 1: MW Ladder. Lane 2: Human Tau (K18) protein, mutant P301L (fibrils) (GTX17675-pro).
GTX17675-PRO Image
TEM image of GTX17675-pro Human Tau (K18) protein, mutant P301L (Pre-formed Fibrils).
GTX17675-PRO Image
TEM image of GTX17675-pro Human Tau (K18) protein, mutant P301L (Pre-formed Fibrils).
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Physical state: | Liquid |
| Type: | Pre-Formed Fibrils |
| Alias: | microtubule associated protein tau , microtubule associated protein tau , DDPAC , FTDP-17 , MAPTL , MSTD , MTBT1 , MTBT2 , PPND , PPP1R103 , TAU |
| Host Cell: | E.coli |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 200 ug |
| Application: | FA |
Additional Text
Gene Name
MAPT
Gene ID
4137
Purification
Ion Exchange
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
Thioflavin T emission curve shows increased fluorescence (correlated to tau protein fibrillation) when active tau PFFs are combined with active tau monomers. *For best results, sonicate immediately prior to use.
Storage Note
Store as concentrated solution. Aliquot and store at -80C. Avoid freeze-thaw cycles.
GTX17675-PRO Datasheet
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