CNTF antibody

Catalogue Number: GTX17692-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:23
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ciliary neurotrophic factor , HCNTF
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Two peptides from human CNTF were mixed and used as immunogens. Both peptides are highly conserved among human and mouse sequences.
Application: ELISA, WB, IHC

Description

Description: The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of the upstream ZFP91 gene and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq, Oct 2010]

Additional Text

Gene ID

1270

Gene Name

CNTF

Uniprot ID

P26441

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

23

Concentration

1 mg/ml

Application Notes

ELISA: 1/500 - 1/2000. IHC: 1/50 - 1/500. WB: 1/500 - 1/2000. Predicted molecular weight: 24 kDa. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.