beta Catenin antibody [CTNNB1/2030R]
Catalogue Number: GTX17706-GTX
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GTX17706 Image
GTX17706 Image
GTX17706 Image
GTX17706 Image
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FACS analysis of HeLa cells using GTX17706 beta Catenin antibody [CTNNB1/2030R]. Blue : Primary antibody Red : Isotype control
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ICC/IF analysis of HeLa cells using GTX17706 beta Catenin antibody [CTNNB1/2030R]. Green : Primary antibody Red : nucleus
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IHC-P analysis of human tonsil tissue using GTX17706 beta Catenin antibody [CTNNB1/2030R].
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IHC-P analysis of human cervical carcinoma tissue using GTX17706 beta Catenin antibody [CTNNB1/2030R].
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| Manufacturer: | GeneTex |
| Preservative: | 0.05% Sodium azide|0.05% Sodium azide |
| Molecular Weight: | 86 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CTNNB , CTNNB1 , MRD19 , armadillo , catenin beta 1 , beta Catenin , Catenin-β , β Catenin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rabbit |
| Clone: | CTNNB1/2030R |
| Isotype: | IgG |
| Immunogen: | Recombinant full-length human β-catenin protein |
| Application: | FC, ICC, IF, IHC-P, PA |
Description
Description: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Additional Text
Gene Name
CTNNB1
Gene ID
1499
Concentration
0.2 mg/ml
Uniprot ID
P35222
Purification
Protein A purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
ICC/IF: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX17706 Datasheet
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