Vimentin antibody [VM452]

Catalogue Number: GTX17723-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:54
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CTRCT30 , HEL113 , VIM , vimentin , Vimentin
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: VM452
Isotype: IgG1
Immunogen: Recombinant full-length human vimentin protein
Application: FC, IHC-P, WB, PA

Description

Description: This gene encodes a type III intermediate filament protein. Intermediate filaments, along with microtubules and actin microfilaments, make up the cytoskeleton. The encoded protein is responsible for maintaining cell shape and integrity of the cytoplasm, and stabilizing cytoskeletal interactions. This protein is involved in neuritogenesis and cholesterol transport and functions as an organizer of a number of other critical proteins involved in cell attachment, migration, and signaling. Bacterial and viral pathogens have been shown to attach to this protein on the host cell surface. Mutations in this gene are associated with congenital cataracts in human patients. [provided by RefSeq, Aug 2017]

Additional Text

Gene Name

VIM

Gene ID

7431

Molecular Weight

54

Uniprot ID

P08670

Purification

Protein A/G Purified

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1-2µg/ml. IHC-P: 1-2µg/ml for 30 minutes at RT. FCM: 1-2µg/10⁶ cells. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.