OPG antibody (Biotin)
Catalogue Number: GTX18068-GTX
GTX18068 Image
GTX18068 Image
GTX18068 Image
ELISA analysis of human OPG recombinant protein (0.2 - 0.4 ng/well) using GTX18068 OPG antibody (Biotin). Working concentration : 0.25- 1.0 ug/ml
GTX18068 Image
ELISA analysis of human OPG recombinant protein(0.2 - 0.4 ng/well) using GTX18068 OPG antibody (Biotin)(detection antibody) at 0.25- 1.0 ug/ml and Anti-Human OPG as a capture antibody.
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 46 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | TNF receptor superfamily member11b , OCIF , OPG , PDB5 , TNFRSF11B , TR1 , Osteoprotegerin , osteoclastogenesis inhibitory factor |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hOPG (human OPG). |
| Application: | ELISA, sELISA, WB |
Description
Description: Osteoprotegerin (OPG) belongs to the TNF receptor (TNFR) family. Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis.
Additional Text
Gene Name
TNFRSF11B
Gene ID
4982
Uniprot ID
O00300
Purification
Affinity Purified
Molecular Weight
46
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.1 - 0.2 µg/mL. ELISA: 0.15 - 0.30 µg/mL. Sandwich ELISA: 0.25 - 1.0 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX18068 Datasheet
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