SR-BI antibody

Catalogue Number: GTX20003-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:57
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:scavenger receptor class B, member 1 , AI120173 , CD36 , Cd36l1 , Chohd1 , Cla-1 , Cla1 , D5Ertd460e , Hdlq1 , Hlb398 , SR-B1 , SR-BI , SRBI , Srb1 , mSR-BI
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509). [UniProt# Q61009]
Application: FC, ICC, IF, IHC-P, IP, WB, IHC-Fr, NT, Inh

Description

Description: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Plays an important role in the uptake of HDL cholesteryl ester.

Additional Text

Gene Name

SCARB1

Uniprot ID

Q61009

Purification

Affinity Purified

Molecular Weight

57

Gene ID

20778

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.

Application Notes

WB: 1:1000 - 1:5000. ICC/IF: 1:50 - 1:1000. IHC-P: 2.5 - 5 µg/ml. FCM: 1:400. IP: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.