CD3 epsilon antibody
Catalogue Number: GTX20022-GTX
| Manufacturer: | GeneTex |
| Preservative: | no preservative|No preservative |
| Molecular Weight: | 23 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD3e molecule , IMD18 , T3E , TCRE |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG1 |
| Immunogen: | Human infant thymocytes and Sezary cells |
| Application: | FC, ICC, IF, IP, WB, RIA, IHC-Fr, IHC |
Description
Description: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
P07766
Purification
Protein A purified
Antibody Clonality
Monoclonal
Molecular Weight
23
Concentration
1 mg/ml
Application Notes
This antibody is not suitable for use on paraffin sections.
Gene ID
915; 916
Gene Name
CD3D, CD3E
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX20022 Datasheet
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