APE1 antibody [13B8E5C2]

Catalogue Number: GTX20194-GTX

Manufacturer:	GeneTex
Preservative:	0.05% Sodium azide\|0.05% Sodium azide
Molecular Weight:	36
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	apurinic/apyrimidinic endodeoxyribonuclease 1 , APE , APE1 , APEN , APEX , APX , HAP1 , REF1
Shipping Condition:	Blue Ice
Unit(s):	50 ul
Host name:	Mouse
Clone:	13B8E5C2
Isotype:	IgG2b
Immunogen:	Purified human APE1 [UniProt# P27695]
Application:	ICC, IF, IHC-P, IP, ChIP, WB, IHC-Fr, EMSA, PLA

Overview
Datasheets

Description

Description: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]

Additional Text

Gene Name

APEX1

Uniprot ID

P27695

Gene ID

328

Purification

Protein G purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

Concentration

1 mg/ml

Application Notes

WB: 1:100 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:100. IHC-Fr: 1:10 - 1:500. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX20194 Datasheet

Price

£558.00

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Quantity
Unit Size

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