PSA antibody [PSA1]

Catalogue Number: GTX20403-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:29
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:kallikrein related peptidase 3 , APS , KLK2A1 , PSA , hK3
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: PSA1
Isotype: IgG1
Immunogen: Full length native protein (purified) (Human)
Application: WB, RIA, IHC-Fr

Description

Description: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

354

Gene Name

KLK3

Uniprot ID

P07288

Purification

Protein A purified

Concentration

5.3 mg/ml

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

29

Application Notes

ELISA: Use at an assay dependant concentration. RIA: Use at an assay dependant concentration. Optimal dilutions/concentrations should be determined by the end user.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.