CD10 antibody [MEM-78] (PE-Cy7)

Catalogue Number: GTX20659-10-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:86
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CALLA , CD10 , CMT2T , MME , NEP , SCA43 , SFE , membrane metalloendopeptidase , Neprilysin
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: MEM-78
Isotype: IgG1
Immunogen: NALM-6 human pre-B cell line
Application: FC

Description

Description: The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]

Additional Text

Gene ID

4311

Gene Name

MME

Uniprot ID

P08473

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.