CD27 antibody [LT27] (PE-Cy7)
Catalogue Number: GTX21091-10-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 29 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD27 , CD27 molecule , S152 , S152. LPFS2 , T14 , TNFRSF7 , Tp55 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | LT27 |
| Isotype: | IgG2a |
| Immunogen: | Human peripheral blood lymphocytes |
| Application: | FC |
Description
Description: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
939
Uniprot ID
P26842
Gene Name
CD27
Antibody Clonality
Monoclonal
Purification
Size-exclusion Chromatography
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.
Application Notes
FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX21091-10 Datasheet
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