CCR8 antibody
Catalogue Number: GTX21666-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.1% Sodium azide |
| Molecular Weight: | 41 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | CC motif chemokine receptor 8,CCCKR8,CCR8,CDw198,CKRL1,CMKBR8,CMKBRL2,CY6,GPRCY6,TER1,CD198,C-C motif chemokine receptor 8 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic peptide VTDYYYPDIFSSPCDAELIQTNGKL-C corresponding to aa 12-36 of human CCR8 |
| Application: | ELISA, FC, IHC-P, WB, NT, Inh |
Description
Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
P51685
Gene ID
1237
Gene Name
CCR8
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
41
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 1:500. IHC-P: 1:125. FCM: 2-6µl/10⁶cells/50-100µl. ELISA: 1:50,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX21666 Datasheet
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