CXCR4 antibody

Catalogue Number: GTX22074-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:40
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:C-X-C motif chemokine receptor 4 , CD184 , D2S201E , FB22 , HM89 , HSY3RR , LAP-3 , LAP3 , LCR1 , LESTR , NPY3R , NPYR , NPYRL , NPYY3R , WHIM , WHIMS
Shipping Condition:Blue Ice
Unit(s): 50 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide sequence corresponding to amino acids 1-14 of human CD184.
Application: ELISA, FC, ICC, IF, IHC-P, WB, IHC-Fr, NT, Inh

Description

Description: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

CXCR4

Uniprot ID

P61073

Gene ID

7852

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

40

Concentration

1 mg/ml

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 1-2 µg/mL. ICC/IF: 2-20 µg/mL. IHC-P: 5 µg/mL. FCM: 0.1 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.