AHR antibody

Catalogue Number: GTX22100-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:95
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:aryl-hydrocarbon receptor , Ah , Ahh , Ahre , In , bHLHe76
Shipping Condition:Blue Ice
Unit(s): 1 ml
Host name: Goat
Clone:
Isotype: IgG
Immunogen: N-terminal sequence of Aryl hydrocarbon Receptor purified from C57BL/6J mice. [UniProt# P30561]
Application: ICC, IF, IHC-P, ChIP, EMSA

Description

Description: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues.

Additional Text

Gene Name

AHR

Uniprot ID

P30561

Gene ID

11622

Purification

Unpurified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

ICC/IF: 5 - 20 µg/ml. IHC-P: 20 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.