TRAIL peptide
Catalogue Number: GTX22436-GTX
| Manufacturer: | GeneTex |
| Shelf Life: | 12 months |
| Preservative: | 0.1% Sodium azide |
| Molecular Weight: | 33 |
| Physical state: | Liquid |
| Type: | Peptide |
| Alias: | TNF superfamily member 10 , APO2L , Apo-2L , CD253 , TL2 , TNLG6A , TRAIL |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Application: | IP |
Description
Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Additional Text
Gene Name
TNFSF10
Gene ID
8743
Uniprot ID
P50591
Concentration
0.2 mg/ml
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
Blocking peptide for rabbit Polyclonal antibody to TRAIL(GTX22435).
Storage Note
Store this product at 4C, DO NOT FREEZE. The product is stable for one year from the date of shipment.
GTX22436 Datasheet
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