APAF1 peptide
Catalogue Number: GTX22446-GTX
| Manufacturer: | GeneTex |
| Shelf Life: | 12 months |
| Preservative: | 0.1% Sodium azide |
| Molecular Weight: | 142 |
| Physical state: | Liquid |
| Type: | Peptide |
| Alias: | apoptotic peptidase activating factor 1 , APAF-1 , CED4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Application: | IP |
Description
Description: This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
APAF1
Gene ID
317
Uniprot ID
O14727
Concentration
0.2 mg/ml
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
Blocking peptide for rabbit Polyclonal antibody to APAF1(GTX22445).
Storage Note
Store this product at 4C, DO NOT FREEZE. The product is stable for one year from the date of shipment.
GTX22446 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations