SRC3 antibody [AX15.3]

Catalogue Number: GTX22782-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:155
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:nuclear receptor coactivator 3 , ACTR , AIB-1 , AIB1 , CAGH16 , CTG26 , KAT13B , RAC3 , SRC-3 , SRC3 , TNRC14 , TNRC16 , TRAM-1 , bHLHe42 , pCIP
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: AX15.3
Isotype: IgG1
Immunogen: GST fusion protein encoding amino acid residues 605-1294 of human AIB1.
Application: IHC-P, IP, ChIP, WB

Description

Description: The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein. [provided by RefSeq, Mar 2010]

Additional Text

Gene Name

NCOA3

Uniprot ID

Q9Y6Q9

Gene ID

8202

Molecular Weight

155

Purification

Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 2µg/ml. IHC-P: 1:10-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.