Ryanodine Receptor antibody [34C]

Catalogue Number: GTX22868-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide|0.05% Sodium azide
Molecular Weight:565
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:ryanodine receptor 1 , CCO , MHS , MHS1 , PPP1R137 , RYDR , RYR , RYR-1 , SKRR
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 34C
Isotype: IgG1
Immunogen: Partially purified chicken pectoral muscle ryanodine receptor.
Application: ICC, IF, IHC-P, IP, WB, IHC-Fr, IHC-Flt

Description

Description: This gene encodes a ryanodine receptor found in skeletal muscle. The encoded protein functions as a calcium release channel in the sarcoplasmic reticulum but also serves to connect the sarcoplasmic reticulum and transverse tubule. Mutations in this gene are associated with malignant hyperthermia susceptibility, central core disease, and minicore myopathy with external ophthalmoplegia. Alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

RYR1

UniProt ID

P21817

Gene ID

6261

Molecular Weight

565

Purification

Protein A purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:5,000. IHC-Fr: 1:1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.