RPSA antibody [MLuC5]
Catalogue Number: GTX23099-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.1% sodium azide|Sodium azide |
| Molecular Weight: | 33 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | ribosomal protein SA , 37LRP , 67LR , ICAS , LAMBR , LAMR1 , LBP , LBP/p40 , LRP , LRP/LR , NEM/1CHD4 , SA , lamR , p40 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Host name: | Mouse |
| Clone: | MLuC5 |
| Isotype: | IgM |
| Immunogen: | Small cell lung carcinoma N592 live cells |
| Application: | FC, ICC, IF, IHC-P, WB, IHC-Fr, NT, Blk, Inh |
Description
Description: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
3921
Gene Name
RPSA
Uniprot ID
P08865
Concentration
0.2 mg/ml
Purification
Purified
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
33
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
GTX23099 Datasheet
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