MVP/LRP antibody [LMR5]
Catalogue Number: GTX23374-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.1% Sodium azide |
| Molecular Weight: | 99 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | major vault protein , LRP , VAULT1 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | 2-8°C |
| Unit(s): | 500 ul |
| Host name: | Rat |
| Clone: | LMR5 |
| Isotype: | IgG |
| Immunogen: | Tissue / cell preparation; 2R120 cell line, derived by stepwise Doxorubicin exposure of the SW-1573 non-small cell lung carcinoma cell line. |
| Application: | FC, IHC-P, IHC-Fr |
Description
Description: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2012]
Additional Text
Gene Name
MVP
Gene ID
9961
Uniprot ID
Q14764
Antibody Clonality
Monoclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
FACS: use at a diluton of 1/20 - 1/30. Cell permeabilization required. IHC-P: use at a diluton of 1/20 - 1/30. IHC-Fr: use at a diluton of 1/20 - 1/30. Optimal dilutions/concentrations should be determined by the end user.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C.
GTX23374 Datasheet
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