SERCA2 ATPase antibody

Catalogue Number: GTX23625-GTX

Manufacturer:GeneTex
Preservative:0.09% sodium azide
Molecular Weight:115
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 , ATP2B , DAR , DD , SERCA2
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: The immunogen recognized by this antibody maps to a region between residue 475 and 525 of human ATPase, Ca++ transporter, cardiac muscle, slow twitch 2 using the numbering given in entry NP_733765.1 (GeneID 488).
Application: IP, ChIP, WB

Description

Description: This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Additional Text

Gene Name

ATP2A2

Uniprot ID

P16615

Gene ID

488

Purification

Affinity Purified

Molecular Weight

115

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Concentration

1 mg/ml

Application Notes

WB: 1:1000 - 1:5000. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.