MCM7 antibody
Catalogue Number: GTX23732-GTX
GTX23732 Image
GTX23732 Image
GTX23732 Image
GTX23732 Image
WB analysis of HeLa cell lysate using GTX23732 MCM7 antibody. Dilution : 0.25 µg/ml
GTX23732 Image
WB analysis of HeLa, 293T, Jurkat, TCMK-1, and NIH3T3 cell lysates using GTX23732 MCM7 antibody. Loading : 50µg Dilution : 2 µg/ml
GTX23732 Image
PLA analysis of HeLa cells using GTX23732 MCM7 antibody and anti-human MCM2 antibody. Red : positive signal Blue : DAPI
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 81 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | minichromosome maintenance complex component 7 , CDC47 , MCM2 , P1.1-MCM3 , P1CDC47 , P85MCM , PNAS146 , PPP1R104 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | The immunogen recognized by this antibody maps to a region between residues 300 and 350 of human Minichromosome Maintenance 7 using the numbering given in entry NP_005907.3 (GeneID 4176). |
| Application: | WB, PLA |
Description
Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]
Additional Text
Gene Name
MCM7
Gene ID
4176
Uniprot ID
P33993
Purification
Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
81
Concentration
1 mg/ml
Application Notes
WB: 1:2000 - 1:10000. PLA: 1:1000 - 1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
GTX23732 Datasheet
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