C4c / C4b antibody (FITC)
Catalogue Number: GTX24216-GTX
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Conjugated |
| Alias: | complement C4B (Chido blood group) , C4B1 , C4B12 , C4B2 , C4B3 , C4B5 , C4BD , C4B_2 , C4F , CH , CO4 , CPAMD3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | C4c complement isolated from complement activated human serum. |
| Application: | IHC-P |
Description
Description: This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq, Jul 2008]
Additional Text
Purification
Purified
Gene ID
100293534; 720; 721
Uniprot ID
P0C0L4, P0C0L5
Gene Name
C4A, C4B, C4B_2
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
IHC-P: 1:50-1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. Protect from light.
GTX24216 Datasheet
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