MCM2 antibody
Catalogue Number: GTX24461-GTX
GTX24461 Image
GTX24461 Image
GTX24461 Image
GTX24461 Image
Left : WB analysis of HeLa cell lysate (in RIPA buffer) using GTX24461 MCM2 antibody. Loading : 50µg Right : IP analysis of HeLa cell lysate using GTX24461 MCM2 antibody. IP reaction : 20µg antibody/7mg lysate Dilution : 0.2 mg/ml
GTX24461 Image
IHC-P analysis of human small cell lung cancer tissue using GTX24461 MCM2 antibody. Dilution : 1 µg/ml
GTX24461 Image
PLA analysis of HeLa cells using GTX24461 MCM2 antibody and anti-human MCM6 antibody. Red : positive signal Blue : DAPI
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 102 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | minichromosome maintenance complex component 2 , BM28 , CCNL1 , CDCL1 , D3S3194 , DFNA70 , MITOTIN , cdc19 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | A 37-amino acid synthetic peptide, which represented a portion of human Minichromosome Maintenance Deficient 2 encoded within exon 2 (LocusLink ID 4171). |
| Application: | IHC-P, IP, WB, PLA |
Description
Description: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. [provided by RefSeq]
Additional Text
Gene Name
MCM2
Uniprot ID
P49736
Gene ID
4171
Purification
Affinity Purified
Molecular Weight
102
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
WB: 1:1000 - 1:10000. IHC-P: 1:2000 - 1:10000. IP: 2 - 5 µg/mg lysate. PLA: 1:1000 - 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
GTX24461 Datasheet
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