PARP (cleaved) antibody (FITC)

Catalogue Number: GTX24831-GTX

Manufacturer:GeneTex
Preservative:0.1% Sodium azide
Molecular Weight:113
Physical state:Liquid
Type:Polyclonal Primary Antibody - Conjugated
Alias:poly(ADP-ribose) polymerase 1 , ADPRT , ADPRT 1 , ADPRT1 , ARTD1 , PARP , PARP-1 , PPOL , pADPRT-1
Shipping Condition:Blue Ice
Unit(s): 500 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: The antiserum was produced against a chemically synthesized peptide corresponding to N-terminus of cleavage site (214/215) of human PARP.
Application: FC, ICC, IF, WB, IHC

Description

Description: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

Additional Text

Gene Name

PARP1

Uniprot ID

P09874

Gene ID

142

Purification

Affinity Purified

Molecular Weight

113

Modification

Cleaved

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles. Protect from light.