HIP1 antibody [4B10]

Catalogue Number: GTX25402-GTX

Manufacturer:	GeneTex
Preservative:	0.1% Sodium azide
Molecular Weight:	116
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	huntingtin interacting protein 1 , HIP-I , ILWEQ , SHON , SHONbeta , SHONgamma
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	4B10
Isotype:	IgG1
Immunogen:	Human 3'-HIP1 (~65 kDa)
Application:	ICC, IF, IHC-P, IP, ChIP, WB

Overview
Datasheets

Description

Description: The product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]

Additional Text

Gene Name

HIP1

Uniprot ID

O00291

Gene ID

3092

Molecular Weight

116

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX25402 Datasheet

Price

£449.00

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