Collagen VII antibody [LH7.2]

Catalogue Number: GTX26312-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:295
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:collagen type VII alpha 1 chain , EBD1 , EBDCT , EBR1 , NDNC8
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: LH7.2
Isotype: IgG1
Immunogen: insoluble fractions of neonatal human foreskin epidermal cells
Application: ELISA, ICC, IF, IHC-P, WB, IHC-Fr, DB

Description

Description: This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq]

Additional Text

Gene ID

1294

Gene Name

COL7A1

Uniprot ID

Q02388

Molecular Weight

295

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-Fr: 1:1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.