pan Cytokeratin antibody [PCK-26]

Catalogue Number: GTX26401-GTX

Manufacturer:	GeneTex
Preservative:	15 mM Sodium azide
Physical state:	Liquid
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	PCK-26
Isotype:	IgG1
Immunogen:	cytokeratin from human epidermis.
Application:	FC, ICC, IF, IHC-P, WB, IHC-Fr, DB, IHC, Multiplex, Blk

Overview
Datasheets

Description

Description: Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratin 5, 6 and 8 are members of the type II neutral-to-basic subfamily. Monoclonal antibodies to cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. PCK-26 facilitates the typing of normal, metaplastic and neoplastic cells and it may aid in the discrimination of carcinomas and non-epithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micro-metastases in lymph nodes and other tissues and for determining the origin of poorly differentiated tumors (1,2).

Additional Text

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1:300. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Short Description

Pan-Cytokeratin antibody [PCK-26] is a mouse monoclonal antibody that detects multiple cytokeratins (i.e., Type II cytokeratins 1, 5, 6, and 8), a group of intermediate filament proteins present in most human epithelial tissues. This reagent is a broad spectrum antibody that reacts with a variety of normal, reactive, and neoplastic epithelial tissues, as well as simple, cornifying, and non-cornifying squamous epithelia and pseudostratified epithelia.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX26401 Datasheet

GTX26401 Reference

Price

£410.00

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