Insulin antibody [K36AC10]

Catalogue Number: GTX26995-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:12
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10
Shipping Condition:Blue Ice
Unit(s): 50 ul
Host name: Mouse
Clone: K36AC10
Isotype: IgG1
Immunogen:
Application: ELISA, FC, IHC-P, RIA, DB

Description

Description: Monoclonal Anti-Insulin may be used for the localization of insulin using RIA, dot blot and immunocytochemistry. Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma. Insulin-specific antibodies prove useful as b-cell and tumor markers using immunohistochemical techniques, and as analytical tools in quantification of the hormone.

Additional Text

Gene Name

INS

Gene ID

3630

Uniprot ID

P01308

Purification

Unpurified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

IHC-P: 1:1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.