Catalogue Number: GTX26995-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 12 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ul |
| Host name: | Mouse |
| Clone: | K36AC10 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | ELISA, FC, IHC-P, RIA, DB |
Description: Monoclonal Anti-Insulin may be used for the localization of insulin using RIA, dot blot and immunocytochemistry. Insulin is one of the major regulatory hormones of intermediate metabolism throughout the body. The biological actions of this hormone involve integration of carbohydrate, protein, and lipid metabolism. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Immunocytochemical investigations have localized insulin in the B or b-cells of pancreatic islets of Langerhans. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma. Insulin-specific antibodies prove useful as b-cell and tumor markers using immunohistochemical techniques, and as analytical tools in quantification of the hormone.
INS
3630
P01308
Unpurified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
IHC-P: 1:1,000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.