TGF alpha antibody

Catalogue Number: GTX27293-GTX

Manufacturer:GeneTex
Preservative:no preservative|No preservative
Molecular Weight:17
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:transforming growth factor alpha , TFGA
Shipping Condition:Blue Ice
Unit(s): 25 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hTGF-alpha (human Transforming Growth Factor-alpha).
Application: ELISA, IHC-P, WB, NT, Inh

Description

Description: Transforming Growth Factor-alpha (TGFa), originally discovered in 1978 in conditioned medium of retrovirus-transformed fibroblasts (ref 1), is a protein that reversibly confers a transformed phenotype upon normal non-neoplastic cells, such as normal rat kidney (NRK) fibroblasts (ref 2). The transforming activity of TGFa was later shown to require the presence of Transforming Growth Factor-beta, which potentiates the action of TGFa via a separate receptor (ref 2-4).

Additional Text

Gene Name

TGFA

Uniprot ID

P01135

Gene ID

7039

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

17

Application Notes

WB: 0.1 - 0.2 µg/mL. ELISA: 0.5 µg/mL. Neutralizing/Inhibition: 0.1 - 0.15 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.