CREB antibody
Catalogue Number: GTX27540-GTX
GTX27540 Image
GTX27540 Image
GTX27540 Image
Anti-CREB is shown to detect CREB-1 present in Raji B cell nuclear extract. Detection occurs using a 1:1,000 dilution of antibody followed by a 1:5,000 dilution of HRP Goat anti Rabbit IgG with visualization via ECL
GTX27540 Image
WB analysis of Raji nuclear extract using GTX27540 CREB antibody. Dilution : 1:1000
| Manufacturer: | GeneTex |
| Preservative: | 0.01% Sodium azide |
| Molecular Weight: | 37 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | cAMP responsive element binding protein 1 , CREB , CREB-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | CREB-1 (p43) peptide corresponding to a region near the N-terminus of the human protein, conjugated to KLH. |
| Application: | ELISA, ChIP, WB, EMSA |
Description
Description: cyclic AMP responsive element binding protein (CREB) is a ubiquitous transcription factor regulated by changes in cyclic AMP (cAMP) levels. CREB binds as a homodimer to CRE sites (cAMP response elements) and belongs to the basic leucine zipper family of DNA binding proteins. Increases in cAMP levels result in the specific phosphorylation of CREB by protein kinase A. Phosphorylated CREB interacts with the transcriptional co-activator CBP (CREB binding protein or p265). It has recently been demonstrated that CREB phosphorylation correlates with light regulated circadian rhythms.
Additional Text
Gene ID
1385
Gene Name
CREB1
Uniprot ID
P16220
Concentration
2.56 mg/mL
Molecular Weight
37
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 1:500-1:1000. ELISA: 1:5000-1:25000. EMSA: 0.5-1 µL per assay. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX27540 Datasheet
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