Catalogue Number: GTX27761-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 12 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | C-PEP-01 |
| Isotype: | IgG1 |
| Immunogen: | Human C-peptide conjugated to bovine serum albumin. |
| Application: | ELISA, ICC, IF, IHC-P, RIA |
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
INS
3630
P01308
Purified
Monoclonal
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
1 mg/ml
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.