Insulin antibody
Catalogue Number: GTX27842-GTX
GTX27842 Image
GTX27842 Image
GTX27842 Image
GTX27842 Image
Insulin antibody detects Insulin protein at cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human pancreas. Insulin stained by Insulin antibody (GTX27842) diluted at 1:50. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX27842 Image
Insulin antibody detects Insulin protein by immunohistochemical analysis. Sample: Paraffin-embedded human tissues. Insulin stained by Insulin antibody (GTX27842) diluted at 1:50. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
GTX27842 Image
Insulin antibody detects Insulin protein by immunohistochemical analysis. Sample: Frozen-sectioned mouse pancreas. Green: Insulin stained by Insulin antibody (GTX27842) diluted at 1:100. Red: C-Peptide antibody [HL1159] (GTX636463) diluted at 1:500. Blue: Fluoroshield with DAPI (GTX30920).
| Manufacturer: | GeneTex |
| Preservative: | 0.09% sodium azide |
| Molecular Weight: | 12 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | insulin , IDDM , IDDM1 , IDDM2 , ILPR , IRDN , MODY10 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 500 ul |
| Host name: | Guinea Pig |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Full length human protein |
| Application: | ICC, IF, IHC-P, IHC-Fr |
Description
Description: After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Additional Text
Gene Name
INS
Gene ID
3630
Uniprot ID
P01308
Concentration
0.2 mg/ml
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
For IHC/ICC: Use at a dilution of 1:50-1:100. Prolonged fixation in buffered formalin can destroy the epitope. Optimal dilutions/concentrations should be determined by the end user.
Purification
Neat Serum
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
GTX27842 Datasheet
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